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Interferon Therapy (HCV)

"Expression of Interferon Receptor Genes in the Liver as a Predictor of Interferon Response in Patients with Chronic Hepatitis C."

Published in Hepatitis Weekly, August 16th, 1999

According to the authors' abstract of an article published in Journal of Medical Virology, "Interferon (IFN) receptor mRNA expression patterns in the liver have been shown to correlate with the effectiveness of IFN therapy in patients with hepatitis C virus (HCV) infection. However, it is not clear to what extent this factor contributes to the short (primary)- and long (sustained)-term results of IFN treatment with respect to biochemical and virological remission. Eighty-two patients who subsequently received lymphoblastoid IFN-alpha therapy underwent liver biopsies before IFN therapy. Possible factors that might correlate with IFN response were chosen and analyzed. The primary...

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