Toxicity

IFN Patients Should be Screened Prior to Therapy

Published in Hepatitis Weekly, August 16th, 1999

Hepatitis patients who are to be treated with interferon therapy should be screened for thyroid- and auto-antibodies before beginning therapy.

Researchers from Germany's University of Bonn also found that such patients should continue to be screened both during and after therapy ("Autoimmunity induced by interferon-alpha therapy for chronic viral hepatitis," Biomed Pharmacother, June 1999;53(5-6):242-254).

Type 1 interferons, which are mostly alpha-interferons (either as single agents or in combination with antiviral drugs), are currently the standard therapy for chronic viral hepatitis B, B/D, and C. Side-effects are not uncommon and include...

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Source: Hepatitis Weekly (1999-08-16)

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