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Virology (HEV)

"Phylogenetic Analysis of Hepatitis E Virus Isolates from India (1976-1993)."

Published in Hepatitis Weekly, August 23rd, 1999

According to the authors' abstract of an article published in Journal of General Virology, "Seventeen Indian hepatitis E virus (HEV) isolates, representing epidemic and sporadic hepatitis E cases during 1976-1991, were sequenced in the RNA polymerase (RNAP) region. Five isolates were also sequenced in the non-structural hypervariable region of open reading frame 1. Open reading frames 2 and 3 were sequenced only for the prototype isolate. On the basis of the comparison of all the available sequences of the conserved RNAP region, the HEV isolates were divided into three genotypes, differing from each other by >15%. Genotype I included African and Asian isolates, whereas II and III...

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