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Non-Alcoholic Steatohepatitis

"Non-Alcoholic Steatohepatitis and Iron: Increased Prevalence of Mutations of the HFE Gene in Non-Alcoholic Steatohepatitis."

Published in Hepatitis Weekly, October 11th, 1999

According to the authors' abstract of an article published in Journal of Hepatology, "Background/Aims: Non-alcoholic steatohepatitis (NASH) is increasingly recognized, and its pathogenesis is believed to involve increased oxidative stress. Elevated levels of serum ferritin and positive liver iron stains are often observed in patients with NASH, and the pathogenesis of liver injury due to iron is also thought to involve oxidative stress. The aim of this study was to determine whether there is an association of NASH and mutations in the HFE gene associated with hereditary hemochromatosis (HHC). Methods: Clinical, laboratory and histopathological data on all 57 subjects...

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