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Interferon Therapy (HCV)

Children with HCV Have Low Virological Responses to IFN

Published in Hepatitis Weekly, November 29th, 1999

by Salynn Boyles, Senior Editor -- A low virological response to interferon was found in children with chronic hepatitis C participating in an Italian study.

Researcher Pasqualina Pensati and colleagues from the University of Naples showed that viremia and transaminase findings were often discordant in children with chronic hepatitis C treated with interferon.

In recent studies, interferon (IFN) was more effective in children than in adults in terms of ALT normalization and HCV RNA clearance. In most of these studies the virological response to IFN was evaluated on the basis of sporadic determinations of serum HCV RNA, but a body of evidence...

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