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Animal Models (Helicobacter typhlonicus)

Immunodeficient Mice Develop Intestinal Disease from Newly Identified Bacteria

Published in Hepatitis Weekly, January 10th, 2000

Researchers have identified a new heliobacter, Helicobacter typhlonicus, which is capable of inducing intestinal disease in mice with immunodeficiency, according to a recent study from the United States.

"Several rodent helicobacters have been associated with chronic active hepatitis or inflammatory bowel disease. Severe combined immunodeficient (SCID) mice appear to be inherently susceptible to disease attributable to these emerging pathogens. With the advent of polymerase chain reaction (PCR) analysis, it has become clear that several as-yet-unidentified Helicobacter species may also colonize rodents, but their capacity to cause disease is unknown,"...

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