Published in Hepatitis Weekly, January 17th, 2000
Liver failure from chronic hepatitis C is the leading indication for liver transplantation in the United States. However, the pathogenesis of liver injury resulting from chronic hepatitis C virus (HCV) infection is not well understood.
"To examine the relationship between HCV replication in liver tissue and hepatocellular injury, a strand-specific in situ hybridization procedure was developed," M. Chang and colleagues from the University of Washington Medical Center wrote ("In situ Distribution of Hepatitis C Virus Replicative-Intermediate RNA in...
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