Antiviral Response
IFN-gamma and iNOS Gene Expression Increased in HCV
Published in Hepatitis Weekly, February 7th, 2000
Pathogenesis of hepatitis C virus (HCV) associated liver injury is thought to be due to the host antiviral immune response. Using a quantitative, competitive RT-PCR technique, S. Schweyer and colleagues from Gottingen, Germany's Georg-August University recently showed that expression of interferon gamma (IFN-gamma) and IFN-gamma inducible type of nitric oxide synthase (iNOS) is increased in homogenized liver tissue of patients with chronic HCV infection.
In this study, the researchers sought to determine the cellular origin of...
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Source: Hepatitis Weekly (2000-02-07)
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