TT Virus

Virus Seen in Italian Blood Donors

Published in Hepatitis Weekly, April 3rd, 2000

TT virus has been found in Italian blood donors with both high and low levels of alanine aminotransferase (ALT).

"A novel non-enveloped DNA virus, called TT virus (TTV), has been reported to be associated with post-transfusion hepatitis of unknown etiology," wrote G. Pisani and colleagues, reporting in the journal Haematologica.

Pisani et al. studied the blood samples of 595 Italian blood donors - some with high, some with low levels of ALT. Serum samples were amplified and sequenced using standard analytical methods.

"The prevalence of TTV in blood donors was 5% ± 1.9% (25 out of 500) with a 95% confidence limit,"...

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Source: Hepatitis Weekly (2000-04-03)

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