Published in Hepatitis Weekly, May 8th, 2000
According to L. Mohr and colleagues at Brown, "The E. coli purine nucleoside phosphorylase (PNP) converts purine analogs into freely diffusible metabolites, which are highly toxic to dividing and nondividing cells."
Investigators analyzed the effect of PNP in three cell HCC cell lines: HepG2, Hep3B, and HuH-7. PNP effects were compared with the effect of using herpes simplex...
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