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Hepatocellular Carcinoma

Phase III Trials Begin for Thymitaq in Liver Cancer

Published in Hepatitis Weekly, August 28th, 2000

Zarix, Inc., Berwyn, Pennsylvania, announced progress on its Thymitaq (nolatrexed dihydrochloride) clinical trial program following recent correspondence with the U.S. Food and Drug Administration (FDA).

Thymitaq, a thymidylate synthase inhibitor, is being developed to treat several different cancers, with an initial emphasis in hepatocellular carcinoma (liver cancer).

Zarix announced that the FDA has indicated that the design of the pivotal Phase III trial for Thymitaq for the treatment of unresectable hepatocellular carcinoma is acceptable. This multi-center clinical study will be conducted as a global program with clinical study sites in the...

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