Published in Hepatitis Weekly, December 4th, 2000
Y.S. Hahn and colleagues at the University of Virginia previously showed that of the major hepatitis C virus (HCV) proteins, only one, the nucleocapsid core protein, can confer on a carrier virus the ability to evade the host animal's immune system (M.K. Large, Y.S. Hahn, et al., J Immunol, 1999;162(2):931+). Because this finding might help explain the long-term viral persistence that makes hepatitis C intractable, this group has now screened for lymphocyte proteins that can interact specifically with the viral core protein.
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