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Liver Cancer

Fewer Immune Cells Seen in HCV-Related Liver Cirrhosis May Increase Risk

Published in Hepatitis Weekly, January 8th, 2001

Individuals with hepatitis C virus (HCV)-related liver cirrhosis have fewer CD56+ T cells and natural killer cells. The shortage of these immune cells may be linked to hepatocellular carcinoma, research investigators report in the journal Hepatology.

The study compared patients with chronic hepatitis C with individuals without HCV.

"The liver mononuclear cells (MNC) of HCV- patients contained 20% CD56+ T cells, whereas the same proportions decreased to 11% in chronic hepatitis livers and to 5% in cirrhotic livers," reported N. Kawarabayashi and colleagues at the National Defense Medical College in...

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