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Mice Inoculated with Hepatitis B Tagged Microspheres Show Good Immune Response

Published in Hepatitis Weekly, February 12th, 2001

- Sonia Nichols, staff medical writer -- Tiny microspheres embedded with hepatitis B surface antigen (HBsAg) may comprise the next generation of drug delivery systems for hepatitis B vaccines, if the latest research being developed in bioengineering labs pans out.

Several research institutions have already delved into the use of these microspheres as adjuvant drug delivery mechanisms for a number of pharmaceuticals. One of the latest studies, performed in the Department of Biotechnological Engineering at Ben Gurion University of Negev, has tested the use of these HBsAg entrapped microscopic orbs on mice.

The group used two sizes of microencapsulated...

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