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Epstein-Barr Virus

Grafts In EBV-Infected Patients Rejected Due To Immunosuppression

Published in Hepatitis Weekly, April 9th, 2001

by Sonia Nichols, staff medical writer - Although liver transplant patients with Epstein-Barr virus (EBV) can be treated with immunosuppressive therapies, their long-term prospects for graft survival are not good, scientists say.

Investigators at the University of Pittsburgh Medical Center in Pennsylvania studied biopsy samples from more than 20 patients with EBV-associated primarily extrahepatic post-transplant lymphoproliferative disease (PTLD).

Almost all of the patients showed signs of acute rejection in liver biopsies, with only four of 24 patients demonstrating no signs of rejection, according to investigators.

"EBV...

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