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Liver Cancer

Testosterone Affects HBV-Related Hepatocellular Carcinoma Risk In Men

Published in Hepatitis Weekly, January 7th, 2002

by Sonia Nichols, senior medical writer - A new Japanese study suggests sex hormones influence the formation of primary liver cancer, or hepatocellular carcinoma (HCC), in men infected with hepatitis B virus (HBV).

Because men develop HCC more often than women do, investigators elected to evaluate the influence of hormones with respect to HCC in infected males. The study, involving more than 4000 male HBV carriers and performed over several years, was designed to evaluate estradiol, testosterone, and genetic changes associated with hormonal factors in men who eventually developed HCC.

"The risk of HCC increased with increasing concentrations of...

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