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Viral Coinfection

HIV Aggravates Chronic Hepatitis C In Injection Drug Users

Published in Hepatitis Weekly, January 21st, 2002

by Sonia Nichols, senior medical writer - Being coinfected with the human immunodeficiency virus (HIV) can worsen the symptoms of chronic hepatitis C in injection drug users, medical researchers have found.

After comparing the effects of hepatitis C virus (HCV) and HIV coinfection in 80 injection drugs users and the same number of HIV negative but HCV positive injection drug users, Vincent Di Martino and colleagues at INSERM, the national research consortium in France, have concluded HIV coinfection increases liver damage and the risk for cirrhosis and death.

Coinfected patients had higher levels of HCV-RNA and lower CD4 T-cell counts, according to...

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