Liver Disease

Phase II Trial Of Actimmune As Antifibrotic Therapy Initiated

Published in Hepatitis Weekly, January 28th, 2002

InterMune, Inc., announced that it has begun enrolling patients in its Phase II clinical trial of Actimmune (interferon (gamma)-1b) injection for the treatment of severe liver fibrosis, or cirrhosis, caused by hepatitis C virus (HCV).

The objective of the study, called AEGIS (Antifibrotic Efficacy Gamma Interferon Study), is to evaluate the safety and antifibrotic activity of Actimmune in HCV patients who have failed standard antiviral therapy.

More than 4 million people are affected with HCV in the United States, and current antiviral therapy for HCV infection is effective in only approximately 50% of patients. Because treatment is often not...

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Source: Hepatitis Weekly (2002-01-28)

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