Liver Failure

Blood lactate measurement could lead to earlier identification of transplant candidates

Published in Hepatitis Weekly, March 11th, 2002

Arterial blood lactate measurement could rapidly and accurately identify patients who might die from paracetamol-induced acute liver failure, conclude authors of a study in the February 13, 2002 issue of the Lancet. Its use is likely to improve the speed and accuracy of selection of appropriate patients for transplantation.

King's College Hospital (KCH) selection criteria for emergency liver transplantation in paracetamol-induced acute liver failure are widely used; they include a combination of renal failure, encephalopathy, coagulopathy (blood clotting), or severe acidosis.

However, strategies to improve sensitivity and to facilitate...

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Source: Hepatitis Weekly (2002-03-11)

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