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MIV-210 is antihepatitis B and HIV compound with unique resistance profile

Published in Hepatitis Weekly, April 8th, 2002

Researchers at Medivir AB, Sweden presented results from an evaluation of MIV-210, an inhibitor of hepatitis B virus (HBV) and HIV at the 15th International Conference on Antiviral Research held in Prague.

The nucleoside analogue MIV-210 inhibits HBV and HIV in cell culture and in vivo: Both HIV and HBV develop resistance to present therapies but MIV-210 shows effect against such resistant virus in cell cultures.

In a hepatitis B in vivo model MIV-210 shows a more potent effect than lamivudine, the only antiviral drug presently on the market for hepatitis B treatment. In an in vivo model for HIV infection MIV-210 is about 10 times more potent then...

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