Chronic Hepatitis B

COX-2 levels persist in hepatitis B patients despite therapeutic response

Published in Hepatitis Weekly, April 22nd, 2002

by Sonia Nichols, senior medical writer - Cyclooxygenase levels tend to rise with hepatitis B virus (HBV) infection and don't fall even when an individual achieves therapeutic response after receiving antivirals.

Still, researchers in China don't believe high COX-2 enzyme levels contribute to liver inflammation in patients with chronic hepatitis B.

Using a variety of analytical tools, A.S.L. Cheng and colleagues at Prince Wales Hospital in Hong Kong investigated COX-2 expression in 35 patients diagnosed with hepatitis B and in 14 healthy controls. Their analyses incorporated tests for viral markers as well as the enzyme, and also included an...

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Source: Hepatitis Weekly (2002-04-22)

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