Thalassemia

Iron depletion can reverse cirrhosis in some patients given marrow transplants

Published in Hepatitis Weekly, June 3rd, 2002

by Sonia Nichols, senior medical writer - Cirrhosis reversal may be possible for patients with thalassemia major who are cured after receiving bone marrow transplantations.

Thalassemia, a condition of inadequate hemoglobin metabolism, can create iron accumulation in the liver, leading to iron overload and cirrhosis formation. Hepatitis C virus infection may exacerbate the problem. Now, however, the results of a study performed in Italy indicate iron depletion therapy in combination with antiviral therapy can improve and even reverse cirrhosis in patients cured of thalassemia after receiving bone marrow transplantations.

The study, performed by...

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Source: Hepatitis Weekly (2002-06-03)

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