Hepatocellular Carcinoma

Vaccine incorporating encapsulated cytokines protects against liver cancer recurrence

Published in Hepatitis Weekly, July 22nd, 2002

by Maria G. Essig, MS, ELS, senior medical writer - Rearchers in Japan report that a vaccine containing cytokines encapsulated in biodegradable microparticles demonstrated a protective effect against liver cancer in a mouse model and in human clinical trials.

B.G. Peng and colleagues at the Institute of Physical and Chemical Research (RIKEN) in Japan evaluated vaccines to prevent recurrence of hepatocellular carcinoma. The investigators designed a vaccine containing cytokines encased within particles that degrade over time, providing a slow release of the cytokines rather than bolus release. Encapsulated cytokines included granulocyte-macrophage colony stimulating...

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Source: Hepatitis Weekly (2002-07-22)

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