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Hepatitis B Virus

Potential new treatment described

Published in Hepatitis Weekly, November 11th, 2002

Researchers from the Scripps Research Institute in La Jolla, California report that the compound interleukin-18 (IL-18) may control replication of the hepatitis B virus (HBV) and be an effective therapy for patients already being treated for chronic hepatitis.

Their results appear in the November 2002 issue of the Journal of Virology.

In the study, HBV-infected mice were treated with IL-18 and then monitored for varying levels of HBV DNA in the liver. HBV DNA levels significantly decreased after 4 hours and were almost undetectable after 24 hours.

"In conclusion, our observation that IL-18 can inhibit HBV replication in...

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