Published in Hepatitis Weekly, December 2nd, 2002
"The La protein was recently identified as a host factor potentially involved in the cytokine-induced post-transcriptional down-regulation of hepatitis B virus (HBV) RNA," said S. Horke and colleagues, University of Hamburg. "The La binding site was mapped to a predicted stem-loop structure within a region shared by all HBV RNAs, and it was concluded that the La protein might be an HBV RNA-stabilizing factor."
In their study, Horke's group produced and analyzed La deletion mutants for HBV RNA...
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