Drug Safety
Nanofiltration removes viruses from human immunoglobulin manufacturing process
Published in Hepatitis Weekly, December 16th, 2002
R.W. van Holten and colleagues stated: "Regulatory agencies have mandated that manufacturers of immunoglobulin products incorporate robust viral inactivation or removal steps into their purification processes. We evaluated the effectiveness of incorporating nanofiltration, a generic virus-clearance step, into an existing plasma-fractionation process for a human anti-D immunoglobulin product."
"The nanofiltration process studied utilizes a 180,000-molecular weight...
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Source: Hepatitis Weekly (2002-12-16)
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