Hepatocellular Carcinoma

IFN therapy doesn't prevent liver cancer in HCV-compensated cirrhosis

Published in Hepatitis Weekly, December 30th, 2002

New study data suggest interferon therapy doesn't protect against development of hepatocellular carcinoma in hepatitis C virus-compensated cirrhosis.

"We conducted a randomized study with interferon versus no therapy in hepatitis C virus Child A cirrhosis with abnormal alanine aminotransferase and HCV-RNA positive serum with the aim to investigate the incidence of hepatocellular carcinoma, worsening of cirrhosis's stage and death or orthotopic liver transplantation," wrote G. Testino and colleagues.

"A cohort of 122 patients prospectively followed was analyzed retrospectively to assess the effect of interferon therapy (mean follow-up: 96...

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Source: Hepatitis Weekly (2002-12-30)

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