Pediatrics
Histologic activity of childhood chronic hepatitis B studied
Published in Hepatitis Weekly, December 30th, 2002
"Despite high viral load, children with chronic hepatitis B virus (HBV) infection may lack significant biochemical signs of liver dysfunction. Failure to develop abnormal liver chemistries is probably due to immunologic hyporeactivity. Despite the absence of biochemical abnormalities in these patients, there is still a risk for long-term complications. The pathogenic importance of viral load and genetic variability is less well studied in children than in adults," noted researchers in Sweden.
"We evaluated viremia levels, genotypes, and mutations related to histologic evidence of liver damage in 71 HBV carriers, aged 2 to 18 years, all of non-Swedish origin," wrote...
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Source: Hepatitis Weekly (2002-12-30)
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