HCV Virology

Hepatitis C virus replicates in sweat glands and keratinocytes

Published in Hepatitis Weekly, January 6th, 2003

According to recent research from Spain, "Hepatitis C virus (HCV) replicates in salivary glands of chronic hepatitis C patients and is released into the saliva, suggesting that HCV may replicate in other exocrine glands."

N. Ortiz-Movilla and colleagues report they have now demonstrated this.

"The presence of positive and negative HCV RNA strands was demonstrated by in situ hybridization, and of HCV core protein by immunohistochemistry, in sweat glands and keratinocytes in healthy skin biopsies from 15 patients with chronic hepatitis C and 10 anti-HCV negative patients with chronic liver disease," the researchers said.

"Positive...

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Source: Hepatitis Weekly (2003-01-06)

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