Hepatitis C Therapy
Early virological response may predict response to interferon treatment
Published in Hepatitis Weekly, January 13th, 2003
"Alpha interferon therapy of chronic hepatitis C is typically accompanied by a biphasic decrease in hepatitis C virus (HCV) RNA levels: an initial rapid decline during the first 24 to 48 hours, and a second more gradual decline during the following weeks. The rate of second-phase decline correlates with ultimate response to interferon treatment. Thus, assessment of early virological response (EVR) may predict outcome," Baylor University hepatologists say.
G.L. Davis and colleagues combined "data from two large clinical trials of peginterferon and ribavirin ... and analyzed [them] to determine the optimal definition of an EVR which, if not achieved, was associated...
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Source: Hepatitis Weekly (2003-01-13)
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