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Hepatitis B Genomics

Most hepatitis B-infected inhabitants of Malawai carry unique subtype

Published in Hepatitis Weekly, February 3rd, 2003

Researchers from Japan have discovered a unique hepatitis B virus subtype among the carrier population of Malawi.

"Hepatitis B virus (HBV) genotypes have distinct geographical distribution. HBV sequences among hepatitis B carriers in Malawi have not been evaluated thus far. HBsAg serotype and genotype of HBV was determined in 20 serum samples from Malawian chronic HBV carriers, and two complete genomes and 13 entire pre-S2/S genes were sequenced directly."

"Genotype A HBV isolates were found in all of the samples, and serotype with adw2 and ayw2 were detected in three and 17 samples, respectively. In phylogenetic analyses, two complete genomes...

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