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Hepatitis C/HIV Coinfection

Prolonged HAART may cause higher hepatitis C load in HIV coinfected

Published in Hepatitis Weekly, February 10th, 2003

by Sonia Nichols, senior medical writer - Long-term use of highly active antiretroviral therapy (HAART) may be responsible for raising hepatitis C virus (HCV) loads in patients coinfected with human immunodeficiency virus (HIV).

Researchers at Stanford University School of Medicine in California have detected higher HCV viral loads and greater quasispecies diversity in such individuals, according to a report in the February 2003 edition of Journal of Virology.

"Three cohorts of coinfected patients were analyzed retrospectively over a period of 7 to 10 months: group A was antiretroviral drug naive at baseline and then on HAART for the remainder...

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