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Evolution of hepatitis C virus in blood donors differs from that of recipients

Published in Hepatitis Weekly, March 31st, 2003

The evolution of hepatitis C virus in blood donors differs from that of recipients.

"This paper describes the study of hepatitis C virus (HCV) evolution in the largest cohort of HCV-infected blood donors (BDs)/blood recipients (BRs) reported to date (25 pairs)," according to research from France.

"A molecular analysis of partial sequences in the Ell (envelope) and NS5-B (polymerase) genes was performed. Phylogenetic reconstruction showed that the evolution of dominant strains was qualitatively and quantitatively different in BDs and BRs," stated J.F. Cantaloube and colleagues, University de la Mediterranee, Faculty of Medicine.

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