Hepatitis C Therapy
Subgenomic replicons used to isolate, characterize PI-resistant mutants
Published in Hepatitis Weekly, April 28th, 2003
"Potent and selective inhibitors of this enzyme have been identified and shown to inhibit HCV replication in tissue culture. The optimization of these inhibitors for clinical development would greatly benefit from in vitro systems for the identification and the study of resistant variants," they said.
C. Trozzi and colleagues have used "HCV subgenomic replicons to isolate and characterize mutants resistant to a protease inhibitor."
"Taking...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Hepatitis Weekly
Source: Hepatitis Weekly (2003-04-28)
More Articles from Hepatitis Weekly
- Disease Transmission
15% Prevalence of chronic HBV infection found in blood donors in Kumasi, Ghana - Immunology
Neutrophils, IFN-gamma limit mouse hepatitis virus replication in CNS - HIV/Hepatitis Coinfection
Hepatitis prevalence not linked to HIV rates - Hepatitis B Vaccine
Hepatitis B virus evades immune system by viral apoptotic mimicry - Pharmacogenetics
CD81-binding site mutations don't appear to affect interferon treatment - Viral Genetics
Stem-loop structures needed for expression of full-length HCV genome identified - More from this issue of Hepatitis Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
