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Hepatitis B Vaccine

Hepatitis B virus evades immune system by viral apoptotic mimicry

Published in Hepatitis Weekly, April 28th, 2003

The hepatitis B virus may evade attack by the immune system through a strategy of viral apoptotic mimicry.

"The co-existence of viruses and organisms for millions of years has influenced the evolution of both. Various viral strategies to enter a host and take over the control of cells to produce virus progeny have developed. Several antiviral (immune) responses have also been developed," researchers in Belgium report.

"The apoptotic death program is a conserved feature of eukaryotic cells," said Peter Vanlandschoot and Geert Leroux-Roels at Ghent University Hospital. "In multicellular organisms the binding and engulfment of apoptotic material is...

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