Autoimmune Disorder
Patients with autoimmune hepatitis form CK19-specific T cells
Published in Hepatitis Weekly, June 30th, 2003
"Recently we have demonstrated the existence of anti-cytokeratin 19 (CK19) antibodies in sera of patients with autoimmune hepatitis (AIH). In the present study, we examined the existence of T lymphocytes specific for CK19 in patients with AIH. The frequency of responders having CK19-specific T lymphocytes was significantly higher in AIH patients than in chronic hepatitis C (CH-C) patients and normal subjects," researchers in Japan report.
"Furthermore, the stimulation index of proliferative responses of peripheral blood mononuclear cells (PBMCs) was significantly higher in AIH patients...
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Source: Hepatitis Weekly (2003-06-30)
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