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Oncology

Alpha-fetoprotein has more validity in nonviral liver cancer diagnoses

Published in Hepatitis Weekly, August 4th, 2003

Alpha-fetoprotein has more validity in nonviral liver cancer diagnoses.

"With the widespread use of ultrasonography (US) and computerized tomography (CT), the usefulness of alpha (a)-fetoprotein assay in the diagnosis of hepatocellular carcinoma (HCC) has decreased. The aim of our study was to evaluate the best cut-off value for serum a-fetoprotein to discriminate between liver cirrhosis (LC) and HCC and the factors influencing levels in a Sicilian population. Three hundred and seventy-two patients with LC and 197 with HCC-associated LC were studied," according to a study from Italy.

"The etiology was: HCV in 288 cases (774%) of LC and 147 cases...

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