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Liver Transplantation

Amphotericin B lipid complex superior to standard agent for IA treatment

Published in Hepatitis Weekly, August 25th, 2003

A lipid complex of amphotericin B is more effective than the standard formulation against invasive aspergillos (IA).

In liver transplant recipients, the development of IA "is associated with poor response rates and a very high mortality rate, despite administration of therapy with conventional amphotericin B," scientists in the United States explained.

P.K. Linden and colleagues at the University of Pittsburgh "conducted a single-center, retrospective study to compare the outcome of liver transplant recipients with IA who received amphotericin B lipid complex (ABLC) or conventional amphotericin B."

"IA was present in 12...

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