Vector-borne Disease

Heterologous flaviviruses alter the outcomes of human yellow fever infections

Published in Hepatitis Weekly, September 1st, 2003

Heterologous flaviviruses alter the outcomes of human yellow fever infections.

According to recent research published in the American Journal of Tropical Medicine and Hygiene, "using a recently described hamster model of severe yellow fever (YF), we examined the hypothesis that prior infection with heterologous flaviviruses protects against severe or fatal YF. Hamsters were singly or sequentially infected with Japanese encephalitis, St. Louis encephalitis, West Nile, and/or dengue-1 viruses, and then challenged with a virulent strain of yellow fever virus (YFV)."

"In contrast to control (naive) hamsters, many of which appeared clinically ill...

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Source: Hepatitis Weekly (2003-09-01)

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