Immunology
Chromatin antibodies associate with autoimmune hepatitis pathology
Published in Hepatitis Weekly, September 1st, 2003
"Our aims were to determine the frequency and prognostic implications of antibodies to chromatin in autoimmune hepatitis. Three hundred seventy-one serum samples from 172 patients were tested by enzyme-linked immunosorbent assay. Sixty-seven patients (39%) had antibodies to chromatin," according to researcher writing in the journal Digestive Diseases and Sciences.
"Percent positivity was greater in men than women (58% vs. 34%, P=0.008), and seropositivity was associated with higher serum levels of gamma-globulin and immunoglobulin G. Antibodies to chromatin disappeared in 25...
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Source: Hepatitis Weekly (2003-09-01)
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