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Hepatitis C Virus

HCV RNA can be detected by polymerase chain reaction in embedded samples

Published in Hepatitis Weekly, November 17th, 2003

HCV RNA can be detected by polymerase chain reaction in embedded samples.

According to researchers in Germany, "we examined the feasibility of detecting hepatitis C virus (HCV) RNA in formalin-fixed, paraffin-embedded (FFPE) specimens obtained by thin-needle biopsy (TNB). Specimens obtained by large-needle biopsy (LNB) and unfixed frozen tissue served as controls. A total of 23 biopsy specimens, 13 obtained by TNB and 10 by LNB, from 20 patients with chronic hepatitis C were included in the study."

"HCV RNA was detected by nested reverse transcription-polymerase chain reaction (RT-PCR)," wrote S. Vogt and colleagues, Otto Von Guericke University,...

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