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Kidney Disease

Risk for interferon-related kidney failure warrants close patient management

Published in Hepatitis Weekly, November 17th, 2003

Risk for interferon-related kidney failure warrants close patient management.

According to a study from Saudi Arabia, "hepatitis C virus (HCV) infection is the most common cause of chronic liver disease, cirrhosis, and hepatocellular carcinoma worldwide. Recombinant interferon alpha (IFN-alpha) is currently the recommended therapy for patients with HCV-induced chronic liver disease. A flu-like syndrome and depression are the most common side effects of IFN-alpha therapy."

"Severe renal adverse effects-including nephrotic syndrome and acute renal failure-are, fortunately, rare, but may be life-threatening; these are often reversible following prompt...

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