Published in Hepatitis Weekly, December 1st, 2003
"The filamentous fungus Aspergillus niger was transformed with the hepatitis B virus S gene encoding the major viral envelope protein under control of the constitutive A. nidulans glyceraldehyde-3-phosphate dehydrogenase (gpdA) promoter. Approximately seven copies of the expression cassette were integrated on the genome, resulting in high-level transcription of the S gene," researchers in South Africa report.
"Production of the 24-kDa S protein and a 48-kDa S protein dimer...
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