Published in Hepatitis Weekly, December 29th, 2003
"PTLDs represent life-threatening complications of bone marrow and solid organ transplantation (SOTx). These are B-cell malignancies triggered by EBV infection in chronically immunosuppressed (IS) recipients," investigators in the United States report.
"Immunosuppressed EBV seronegative (EBV-) organ recipients are at highest risk of developing PTLD, owing to the lack of anti-EBV memory T cells to control subsequent EBV challenges. Our aim...
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