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Hepatitis B Vaccine

Hepatitis B DNA vaccine induces protective responses in non-responders

Published in Hepatitis Weekly, January 26th, 2004

Hepatitis B DNA vaccine induces protective antibody responses in human non-responders to conventional vaccination.

According to recent research from the United States, "A novel DNA vaccine against hepatitis B virus was administered intra-epidermally by particle-mediated epidermal delivery (PMED) to 16 human subjects who demonstrated absent or non-sustainable responses to conventional hepatitis B vaccination. Eleven subjects received three doses of vaccine at 56-day intervals, and five subjects received only a single vaccination. Each dose of vaccine contained 4 microgram of plasmid DNA encoding the hepatitis B surface antigen (HBsAg)."

"The vaccine...

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