Chronic Liver Disease
Interferon-gamma-inducible protein 10 denotes HCV-linked liver status
Published in Hepatitis Weekly, February 9th, 2004
According to published research from Australia, "the factors influencing lymphocyte trafficking to the liver lobule during chronic hepatitis C virus (HCV) infection are currently not well defined. Interferon-gamma-inducible protein 10 (IP-10), a chemokine that recruits activated T lymphocytes, has recently been shown by in situ hybridization to be expressed in the liver during chronic HCV infection. This study sought to define the cellular source of IP-10 in the liver by immunohistochemistry, to examine the expression of its receptor, CXCR3, on T lymphocytes isolated from blood and liver tissue, and...
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Source: Hepatitis Weekly (2004-02-09)
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