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Addiction Medicine

Alcohol has a dose-dependent effect on endothelial adhesion molecules

Published in Hepatitis Weekly, February 9th, 2004

Alcohol has a dose-dependent effect on endothelial adhesion molecules.

"Endothelial adhesion molecules (AM) play an important role in the pathogenesis of several diseases namely infections, neoplasms and chronic inflammatory diseases. Because alcoholic hepatitis and even atherosclerosis are considered as inflammatory diseases and ethanol may modulate inflammatory response, several researchers have investigated the link between ethanol consumption, endothelial AM and the development of both processes.

"In vitro, animal and human studies have analyzed the effects of ethanol and non-alcoholic components of alcoholic beverages on inflammatory biomarkers...

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