Viral Genomics
Denaturing high-performance liquid chromatography can do HCV genotyping
Published in Hepatitis Weekly, March 8th, 2004
According to a study from the United States, "determination of the hepatitis C virus (HCV) genotype for infected patients increasingly has become accepted as the standard of care. Genotype assignment helps in assessing disease prognosis and assists in establishing the appropriate duration of treatment. The great genetic diversity of HCV, with 11 major genotypes and >70 subtypes, contributes to the technical difficulty of genotype testing."
"While the ''gold standard'' for testing is nucleic acid sequencing, a variety of hybridization assays, including the line probe assay,...
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Source: Hepatitis Weekly (2004-03-08)
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