Transfusion Medicine

Hepatitis C virus variants may not associate with extent of pathogenesis

Published in Hepatitis Weekly, April 12th, 2004

Hepatitis C virus variants may not associate with extent of pathogenesis.

"Variants of hepatitis C virus (HCV) from a single infected blood donor and 13 viremic recipients who were traced were examined by sequencing and cloning to determine the extent of virus diversity in hypervariable region 1. Serum-derived viral isolates were studied from the donor when his HCV infection was discovered in 1993, in his recipients that year (0.3-5 years post-transfusion) and 5 years later in the donor and six viremic recipients who were still alive," researchers in Sweden report.

"Viral variants of broad diversity were readily demonstrated in the baseline samples...

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Source: Hepatitis Weekly (2004-04-12)

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