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Cholestatic Hepatitis

Liver graft failure occurs despite antiviral prophylaxis

Published in Hepatitis Weekly, April 19th, 2004

Liver graft failure occurs despite antiviral prophylaxis.

According to a study from Japan, "recurrence of hepatitis C virus after liver transplantation is common and cholestatic hepatitis occurs in approximately 10% of the patients and leads to accelerated graft failure and death.

"A 47-year-old man underwent living donor liver transplantation for hepatitis C-related liver cirrhosis. Pre-emptive antiviral therapy was started using interferon-alpha2b (6 MU x 3 per week) and ribavirin (600mg per day) 2 months after living donor liver transplantation," wrote J. Kaneko and colleagues, University of Tokyo, Graduate School of Medicine.

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